Dr. Shippy Approved
Nrf2 Prime is designed to activate the Nrf2 genetic pathway. This pathway regulates the production of important molecules that impart antioxidant activity, such as glutathione and superoxide dismutase (SOD).
It also regulates the production of detoxification enzymes, including glutathione S-transferase, and downregulates signaling factors such as NF-ϰB. Each ingredient in this formula is backed by extensive research in peer-reviewed journals.
Nrf2 (NF-E2-related factor 2), a transcription factor in humans that is encoded by the NFE2L2 gene, regulates the expression of a set of antioxidant and detoxifying genes.
This action stabilizes Nrf2, allowing it to accumulate in the nucleus and bind to the antioxidant response element (ARE) located in the enhancers of its target genes.
Under this circumstance, Nrf2 then upregulates a variety of antioxidant enzymes and detoxifying proteins.
A variety of natural substances have been shown to influence the Nrf2 pathway:
Glucoraphanin, a naturally occurring isothiocyanate derived from broccoli, is hydrolyzed into sulforaphane (SFN) upon consumption. SFN induces phase 2 cytoprotective enzymes, supporting the body’s cellular response systems.
Pterostilbene (PTS) is a naturally occurring phenolic compound/ analog of resveratrol that has demonstrated cytotoxic, cytokine inhibiting, and antioxidant properties.
Curcumin’s array of biological activities stems from its cytokine balancing activity, antioxidant properties, and induction of phase 2 detoxifying enzymes such as heme oxygenase-1 (HO-1).
Overall, evidence indicates that curcumin exhibits its beneficial effect against oxidative stress through various cellular signaling pathways, including hepatic Nrf2/ARE/Keap1 signaling.*
Other Ingredients: Capsule (hypromellose and water), stearic acid, magnesium stearate, and silica.
DIRECTIONS: Take one to two capsules daily, or as directed by your healthcare practitioner. Consult your healthcare practitioner prior to use. Individuals taking medication, especially blood thinners or cancer treatment, should discuss potential interactions with their healthcare practitioner. Do not use if tamper seal is damaged.
STORAGE: Keep closed in a cool, dry place out of reach of children.
DOES NOT CONTAIN: Wheat, gluten, yeast, soy, animal or dairy products, fish, shellfish, peanuts, tree nuts, egg, ingredients derived from genetically modified organisms (GMOs), artificial colors, artificial sweeteners, or artificial preservatives.
What makes my supplements different?
- Evidence-based, real health solutions
- Pharmaceutical grade therapeutic formulas
- Highest manufacturing standards
- Ingredients tested for purity, quality, potency, and composition
- Best manufacturers from all over the USA
Therapeutic formulas for best results.
As a Board-Certified Internal Medicine physician, I offer pharmaceutical grade nutritional supplements. This means they are typically stronger in potency and higher in quality than supplements you’ll find in most retail or online stores. It also means you can expect to achieve greater results.
Quality ingredients and formulations. Pure and simple.
The ingredients have been tested for purity, quality, potency, and composition, so you can trust the identity of each formula. It’s so important to know that what you are putting in your body is the purest form and highest quality. I would want nothing less for myself, my patients, or for you.
The ingredients and formulations in my products are from wholesome, pure, clean sources, and in their most bioavailable forms for maximum effectiveness. This means that they are in the form that is best absorbed and utilized by your body.
It’s not just what’s in the supplement that matters - what's not in the supplement is just as important. Many of my patients, including myself, have food allergies or sensitivities. None of my supplements contain gluten, dairy, GMOs, preservatives, dyes or toxins.
There are a couple of rare exceptions where products contain trace amounts of egg and a few contain tree nuts. All ingredients are clearly indicated on the product pages. Be sure to read carefully if you have any know food allergies or sensitivities.
Highest manufacturing standards.
The supplements in my store are manufactured in facilities that are strictly controlled by rigorous standards that meet cGMPs, and routinely pass FDA and third-party audits. Materials go through laboratory testing from raw source to the finished product…to bottling and labeling.
I offer the best of the best, from all over the country.
In order to provide a comprehensive array of supplements I don’t rely on just one manufacturer. I recognize that some have better sources and formulations in specific areas than others, and I only select the best of the best. This means, you don’t have to go researching and searching – I've done all the leg work for you.
It’s taken many years of research, trial, implementation, and relationship building to bring what I am offering to you and to my patients. I also stay on top of the latest advancements in formulas, science and industry news to continue to offer the highest quality of innovative supplements. This means you will see changes in offerings to reflect cutting edge solutions.
Evidence-based. Supplements that offer real health solutions.
I personally select every product on my store. Ultimately, it is the science, research and clinical testing that drives my choices and recommendations.
Also, I choose what works. In my years of experience, I have observed the positive outcomes of many of these formulas with patients. In my practice I look for the most natural methods to address health concerns - and often key nutrients and supplements are a huge part of the solution.
I am truly passionate about helping you achieve your best health. I hope you find the nutritional supplements you are looking for and that you are satisfied with your purchase. My helpful staff is committed to providing excellent customer service. Please email them at email@example.com if you have any questions.
Continental US Orders
Free Shipping for Orders $99 and over
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